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The loop between helix 4 and helix 5 in the monocarboxylate transporter MCT1 is important for substrate selection and protein stability

Galic, S; Schneider, Hans-Peter; Broer, Angelika; Deitmer, Joachim W; Broer, Stefan

Description

Transport of lactate, pyruvate and the ketone bodies acetoacetate and β-hydroxybutyrate, is mediated in most mammalian cells by members of the monocarboxylate transporter family (SLC16). A conserved signature sequence has been identified in this family,

CollectionsANU Research Publications
Date published: 2003
Type: Journal article
URI: http://hdl.handle.net/1885/88566
Source: Biochemical Journal
DOI: 10.1042/BJ20030799

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