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What we dont know about the Structure of Ryanodine receptor Calcium release channels

Dulhunty, Angela; Pouliquin, Pierre


1. The ryanodine receptor (RyR) is the Ca2+ release channel in the sarcoplamic reticulum of skeletal and cardiac muscle and is essential for respiration and heart beat. The RyR channel releases Ca2+ from intracellular stores in a variety of other cell types, where it normally coexists with the inositiol 1,4,5-trisphosphate receptor (IP3R). The RyR and IP3R, forming a superfamily of homotetrameric ligand-gated intracellular Ca2+ channels, serve discrete functions: they can be located in...[Show more]

CollectionsANU Research Publications
Date published: 2003
Type: Journal article
Source: Clinical and Experimental Pharmacology and Physiology
DOI: 10.1046/j.1440-1681.2003.03904.x


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