What we dont know about the Structure of Ryanodine receptor Calcium release channels
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Dulhunty, Angela; Pouliquin, Pierre
Description
1. The ryanodine receptor (RyR) is the Ca2+ release channel in the sarcoplamic reticulum of skeletal and cardiac muscle and is essential for respiration and heart beat. The RyR channel releases Ca2+ from intracellular stores in a variety of other cell types, where it normally coexists with the inositiol 1,4,5-trisphosphate receptor (IP3R). The RyR and IP3R, forming a superfamily of homotetrameric ligand-gated intracellular Ca2+ channels, serve discrete functions: they can be located in...[Show more]
Collections | ANU Research Publications |
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Date published: | 2003 |
Type: | Journal article |
URI: | http://hdl.handle.net/1885/88545 |
Source: | Clinical and Experimental Pharmacology and Physiology |
DOI: | 10.1046/j.1440-1681.2003.03904.x |
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