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Murine filariasis: interleukin 4 and interleukin 5 lead to containment of different worm developmental stages

Volkmann, Lars; Bain, Odile; Saeftel, Michael; Specht, Sabine; Fischer, Kerstin; Brombacher, Frank; Matthaei, Klaus; Hoerauf, Achim

Description

We compared the impact of IL-4 and IL-5 deficiency during the fully permissive infection of BALB/c mice with the rodent filaria Litomosoides sigmodontis. IL-5, in contrast to IL-4, is crucial for the containment of adult worms during short- and long-term

dc.contributor.authorVolkmann, Lars
dc.contributor.authorBain, Odile
dc.contributor.authorSaeftel, Michael
dc.contributor.authorSpecht, Sabine
dc.contributor.authorFischer, Kerstin
dc.contributor.authorBrombacher, Frank
dc.contributor.authorMatthaei, Klaus
dc.contributor.authorHoerauf, Achim
dc.date.accessioned2015-12-13T23:14:17Z
dc.date.available2015-12-13T23:14:17Z
dc.identifier.issn0300-8584
dc.identifier.urihttp://hdl.handle.net/1885/88534
dc.description.abstractWe compared the impact of IL-4 and IL-5 deficiency during the fully permissive infection of BALB/c mice with the rodent filaria Litomosoides sigmodontis. IL-5, in contrast to IL-4, is crucial for the containment of adult worms during short- and long-term
dc.publisherSpringer
dc.sourceMedical Microbiology and Immunology
dc.subjectKeywords: interleukin 4; interleukin 4 receptor; interleukin 5; animal cell; animal experiment; animal model; conference paper; controlled study; eosinophil; female; filariasis; infection sensitivity; inflammation; knockout mouse; male; microfilariasis; mouse; neut Eosinophils; Interleukin-4; Interleukin-5; Murine filariasis; Neutrophils
dc.titleMurine filariasis: interleukin 4 and interleukin 5 lead to containment of different worm developmental stages
dc.typeJournal article
local.description.notesImported from ARIES
local.description.refereedYes
local.identifier.citationvolume192
dc.date.issued2003
local.identifier.absfor060599 - Microbiology not elsewhere classified
local.identifier.ariespublicationMigratedxPub18249
local.type.statusPublished Version
local.contributor.affiliationVolkmann, Lars, Bernhard Nocht Institute for Tropical Medicine
local.contributor.affiliationBain, Odile, Museum National d'Histoire Naturelle
local.contributor.affiliationSaeftel, Michael, Bernhard Nocht Institute for Tropical Medicine
local.contributor.affiliationSpecht, Sabine, Bernhard Nocht Institute for Tropical Medicine
local.contributor.affiliationFischer, Kerstin, Bernhard Nocht Institute for Tropical Medicine
local.contributor.affiliationBrombacher, Frank, University of Cape Town
local.contributor.affiliationMatthaei, Klaus, College of Medicine, Biology and Environment, ANU
local.contributor.affiliationHoerauf, Achim, Bernhard Nocht Institute for Tropical Medicine
local.bibliographicCitation.startpage23
local.bibliographicCitation.lastpage31
dc.date.updated2015-12-12T08:38:15Z
local.identifier.scopusID2-s2.0-0344211404
CollectionsANU Research Publications

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