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Murine filariasis: interleukin 4 and interleukin 5 lead to containment of different worm developmental stages

Volkmann, Lars; Bain, Odile; Saeftel, Michael; Specht, Sabine; Fischer, Kerstin; Brombacher, Frank; Matthaei, Klaus; Hoerauf, Achim


We compared the impact of IL-4 and IL-5 deficiency during the fully permissive infection of BALB/c mice with the rodent filaria Litomosoides sigmodontis. IL-5, in contrast to IL-4, is crucial for the containment of adult worms during short- and long-term

CollectionsANU Research Publications
Date published: 2003
Type: Journal article
Source: Medical Microbiology and Immunology


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