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Mechanisms of accelerated immune-mediated diabetes resulting from islet β cell expression of a Fas ligand transgene

Silva, Diego; Petrovsky, Nikolai; Socha, L; Slattery, Robyn; Gatenby, Paul; Charlton, Brett

Description

Nonobese diabetic (NOD) mice transgenic for Fas ligand (FasL) on islet β cells (HIPFasL mice) exhibit an accelerated diabetes distinct from the normal autoimmune diabetes of NOD mice. This study was undertaken to define the mechanism underlying accelerat

CollectionsANU Research Publications
Date published: 2003
Type: Journal article
URI: http://hdl.handle.net/1885/88409
Source: Journal of Immunology

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