Petrovsky, Nikolai; Socha, L; Silva, Diego; Grossman, Arthur Robert; Metz, Christine; Bucala, Richard
In humans, maximal expression of T helper 1 cytokines coincide with the nocturnal nadir of plasma cortisol, whereas T helper 2 cytokine responses are dominant during day-time. The pro-inflammatory cytokine, macrophage migration inhibitory factor counter-regulates glucocorticoid-mediated immune suppression. To determine the relationship between cortisol and macrophage migration inhibitory factor, healthy volunteers had blood drawn hourly for 24 h for measurement of plasma cortisol and basal- and...[Show more]
Items in Open Research are protected by copyright, with all rights reserved, unless otherwise indicated.