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A new model of sheep Ig diversification: shifting the emphasis toward combinatorial mechanisms and away from hypermutation

Jenne, C; Kennedy, L; McCullagh, Peter; Reynolds, J


The current model of Ig repertoire development in sheep focuses on the rearrangement of a small number (∼20) of Vλ gene segments. It is believed that this limited combinatorial repertoire is then further diversified through postrearrangement somatic hy

CollectionsANU Research Publications
Date published: 2003
Type: Journal article
Source: Journal of Immunology


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