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Extensive and specific responses of a eukaryote to bacterial quorum-sensing signals

Mathesius, Ulrike; Mulders, S; Gao, Mengsheng; Teplitski, Max; Caetano-Annolles, G; Rolfe, Barry; Bauer, Wolfgang


Many bacteria use N-acyl homoserine lactone (AHL) signals to coordinate the behavior of individual cells in a local population. The successful infection of eukaryotic hosts by bacteria seems to depend particularly on such AHL-mediated "quorum-sensing" regulation. We have used proteome analysis to show that a eukaryotic host, the model legume Medicago truncatula, is able to detect nanomolar to micromolar concentrations of bacterial AHLs from both symbiotic (Sinorhizobium meliloti) and pathogenic...[Show more]

CollectionsANU Research Publications
Date published: 2003
Type: Journal article
Source: PNAS - Proceedings of the National Academy of Sciences of the United States of America
DOI: 10.1073/pnas.262672599


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