Heparanase is involved in the pathogenesis of proteinuria as a result of glomerulonephritis
The β-D-endoglycosidase heparanase has been proposed to be important in the pathogenesis of proteinuria by selectively degrading the negatively charged side chains of heparan sulfate proteoglycans within the glomerular basement membrane. A loss of negati
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|Source:||Journal of the American Society of Nephrology|
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