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Prevention of autoimmune diabetes through immunostimulation with Q fever complement-fixing antigen

Silva, Diego; Charlton, Brett; Cowden, William; Petrovsky, Nikolai


The most promising strategies for prevention of type 1 diabetes seem to be in the categories of immunomodulation (e.g., nondepleting anti-CD3, Diapep, linomide) and/or immunostimulation (e.g., QFA, BCG). We are currently undertaking a research program directed toward better understanding of immunostimulants to help maximize the likelihood of success of future human clinical trials for diabetes prevention. This program is focused on the key areas of optimization of vaccine dose and route of...[Show more]

CollectionsANU Research Publications
Date published: 2003
Type: Journal article
Source: Annals of the New York Academy of Sciences
DOI: 10.1196/annals.1288.072


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