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Physics of Ion Channels

Kuyucak, Serdar; Bastug, Turgut


We review the basic physics involved in transport of ions across membrane channels in cells. Electrochemical forces that control the diffusion of ions are discussed both from microscopic and macroscopic perspectives. A case is made for use of Brownian dynamics as the minimal phenomenological model that provides a bridge between experiments and more fundamental theoretical approaches. Application of Brownian and molecular dynamics methods to channels with known molecular structures is discussed.

CollectionsANU Research Publications
Date published: 2003
Type: Journal article
Source: Journal of Biological Physics
DOI: 10.1023/A:1027309113522


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