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Mice Deficient in Glutathione tranferase Zeta/Maleylacetoacetate Isomerase Exhibit a Range of Pathological Changes and Elevated Expression of Alpha, Mu, and Pi Class Glutathione Transferases

Lim, Cindy; Matthaei, Klaus; Blackburn, Anneke; Davis, Richard; Koina, Mark; Anders, Michael; Board, Philip; Dahlstrom, Jane

Description

Glutathione transferase zeta (GSTZ1-1) is the major enzyme that catalyzes the metabolism of α-halo acids such as dichloroacetic acid, a carcinogenic contaminant of chlorinated water. GSTZ1-1 is identical with maleylacetoacetate isomerase, which catalyzes

CollectionsANU Research Publications
Date published: 2004
Type: Journal article
URI: http://hdl.handle.net/1885/87448
Source: American Journal of Pathology

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