Developmentally essential protein Flightless I is a nuclear receptor coactivator with actin binding activity
Hormone-activated nuclear receptors (NR) activate transcription by recruiting multiple coactivator complexes to the promoters of target genes. One important coactivator complex includes a p160 coactivator (e.g., GRIP1, SRC-1, or ACTR) that binds directly
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|Source:||Molecular and Cellular Biology|
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