Two major classes of target site insensitivity mutations confer resistance to organophosphate and carbamate insecticides
Interspecific comparisons of bioassay and biochemical data suggest two major patterns of target site resistance to carbamates and organophosphates. Pattern I resistance, which is generally more effective for carbamates, has been shown in two sub-species of mosquitoes to be due to a particular Gly-Ser mutation in the oxyanion hole within the active site of one of their two acetylcholinesterase enzymes. Intriguingly, different substitutions at the equivalent site confer organophosphate hydrolytic...[Show more]
|Collections||ANU Research Publications|
|Source:||Pesticide Biochemistry and Physiology|
|01_Russell_Two_major_classes_of_target_2004.pdf||204.66 kB||Adobe PDF||Request a copy|
Items in Open Research are protected by copyright, with all rights reserved, unless otherwise indicated.