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Antibiotics from Australian terrestrial invertebrates. Part 1: Antibacterial trinervitadienes from the termite Nasutitermes triodiae

Zhao, Chunjiu; Rickards, Rodney; Trowell, Stephen Charles


The antibacterial activity of an extract of the Australian termite Nasutitermes triodiae (Isoptera: Termitidae) (Froggatt) is due to the presence of a group of trinervitanes, diterpenes unique to termite genera within the subfamily Nasutitermitinae. The major active components are novel hydroxylated 1(15),8(19)-trinervitadienes and the known 1(15),8(9)-trinervitadiene-2β, 3α-diol. This constitutes the first observation of hydroxylation of the trinervitane skeleton at the 5- and 18-positions,...[Show more]

CollectionsANU Research Publications
Date published: 2004
Type: Journal article
Source: Tetrahedron
DOI: 10.1016/j.tet.2004.08.065


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