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Specific Ion Effects: Why the Properties of Lysozyme in Salt Solutions Follow a Hofmeister Series

Bostrom, Mathias; Williams, David; Ninham, Barry

Description

Protein solubility in aqueous solutions depends in a complicated and not well understood way on pH, salt type, and salt concentration. Why for instance does the use of two different monovalent salts, potassium thiocyanate and potassium chloride, produce such different results? One important and previously neglected source of ion specificity is the ionic dispersion potential that acts between each ion and the protein. This attractive potential is found to be much stronger for SCN- than it is for...[Show more]

CollectionsANU Research Publications
Date published: 2003
Type: Journal article
URI: http://hdl.handle.net/1885/86893
Source: Biophysical Journal

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