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Identification of differentially expressed genes representing dendritic cell precursors and their progeny

Wilson, Heather; O'Neill, Helen


The development of dendritic cells (DCs) from hematopoietic progenitors is not well understood. Using a spleen-derived long-term culture (LTC) system, it has been possible to continuously generate DCs from progenitors maintained in culture. The nonadherent LTC-DC population is composed of 2 major subsets. These are the small LTC-DC or DC precursors and their progeny, the large LTC-DCs that phenotypically resemble immature DCs. In this study, subtracted cDNA libraries were generated containing...[Show more]

CollectionsANU Research Publications
Date published: 2003
Type: Journal article
Source: Blood
DOI: 10.1182/blood-2002-08-2426


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