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Dynamics of dendritic cell development from precursors maintained in stroma-dependant long-term cultures

Wilson, Heather; O'Neill, Helen


Two distinct subsets of dendritic cells are produced within the non-adherent cell population of the stroma-dependent long-term culture system. These are the small subset containing dendritic cell precursors and their progeny, large long-term culture-dendritic cells, which resemble immature CD11c+CD11b+MHCIIloCD8α- dendritic cells. The replicative and developmental potential of cells produced in long-term culture were investigated as a model for production of dendritic cells from progenitors....[Show more]

CollectionsANU Research Publications
Date published: 2003
Type: Journal article
Source: Immunology and Cell Biology
DOI: 10.1046/j.0818-9641.2002.01149.x


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