A biotin derivative blocks parasite induced novel permeation pathways in Plasmodium falciparum -infected erythrocytes
The malaria parasite Plasmodium falciparum infects human erythrocytes, and it induces an increased rate of uptake into the infected cell of a range of solutes, including essential nutrients required for parasite development. Several models have been proposed for the mechanism(s) underlying parasite-induced solute uptake, each differing with respect to the site of entry into infected cells. We show that a biotin derivative that is excluded from non-infected erythrocytes gains access to infected...[Show more]
|Collections||ANU Research Publications|
|Source:||Molecular and Biochemical Parasitology|
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