De-ubiquitination and ubiquitin ligase domains of A20 downregulate NF-kB signalling
-
Altmetric Citations
Wen, S; O'Rourke, Karen; Zhou, Honglin; Eby, Michael; Aravind, L; Seshagiri, Somasekar; Wu, Ping-Shi; Wiesmann, Christian; Baker, Rohan; Boone, David; Ma, Averil; Koonin, Eugene; Dixit, Vishva
Description
NF-κB transcription factors mediate the effects of pro-inflammatory cytokines such as tumour necrosis factor-α and interleukin-1β. Failure to downregulate NF-κB transcriptional activity results in chronic inflammation and cell death, as observed in A2
| Collections | ANU Research Publications |
|---|---|
| Date published: | 2004 |
| Type: | Journal article |
| URI: | http://hdl.handle.net/1885/86318 |
| Source: | Nature |
| DOI: | 10.1038/nature02794 |
Download
| File | Description | Size | Format | Image |
|---|---|---|---|---|
| 01_Wen_De-ubiquitination_and_2004.pdf | 598.22 kB | Adobe PDF | Request a copy |
Items in Open Research are protected by copyright, with all rights reserved, unless otherwise indicated.
Updated: 17 November 2022/ Responsible Officer: University Librarian/ Page Contact: Library Systems & Web Coordinator
+61 2 6125 5111
The Australian National University, Canberra
CRICOS Provider : 00120C
ABN : 52 234 063 906
