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Polymorphism of human mu class glutathione transferases

Tetlow, Natasha; Robinson, Anna; Mantle, Tim; Board, Philip

Description

Objectives and methods: A combined database mining approach was used to detect polymorphisms in the mu class glutathione-S-transferase (GST) genes. Although a large number of potential polymorphisms were detected in the five genes that comprise the Mu class GSTs using sequence alignment programs and by searching single nucleotide polymorphism databases, the majority were not validated or detected in three major ethnic populations (African, Southern Chinese and Australian European). Results: Two...[Show more]

CollectionsANU Research Publications
Date published: 2004
Type: Journal article
URI: http://hdl.handle.net/1885/86298
Source: Pharmacogenetics and Genomics
DOI: 10.1097/00008571-200406000-00005

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