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The Flightless I protein and the gelsolin family in nuclear hormone receptor-mediated signalling

Archer, Stuart; Behm, Carolyn; Claudianos, Charles; Campbell, Hugh


The Drosophila melanogaster flightless I protein and its homologues in higher eukaryotes (Flil) are conserved members of the gelsolin family of actin-binding proteins. Members of the gelsolin family generally contain three or six copies of a 125-amino-acid residue gelsolin-related repeating unit, and may contain additional domains including the C-terminal villin-related 'headpiece' or N-terminal extensions such as the leucine-rich repeat of the Flil protein. Numerous studies including work done...[Show more]

CollectionsANU Research Publications
Date published: 2004
Type: Journal article
Source: Biochemical Society Transactions
DOI: 10.1042/BST0320940


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