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A role for niches in the development of a multiplicity of dendritic cell subsets

Despars, Genevieve; O'Neill, Helen


Although most studies on murine dendritic cell (DC) differentiation concentrate on the nature of the DC precursor population and the lineage relationship between DC and other hematopoietic cell types, very little research addresses the nature of the microenvironments necessary for DC hematopoiesis. Evidence supporting a major contribution of niches in DC differentiation within hematopoietic tissues is reviewed. A model is presented that identifies a potential role for multiple hematopoietic...[Show more]

CollectionsANU Research Publications
Date published: 2004
Type: Journal article
Source: Experimental Hematology
DOI: 10.1016/j.exphem.2003.12.004


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