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T Cell Tolerance to a Neo-Self Antigen Expressed by Thymic Epithelial Cells: the Soluble Form Is More Effective Than the Membrane-Bound Form

Zhang, Meifen; Vacchio, Melanie; Vistica, Barbara; Lesage, Sylvie; Egwuagu, Charles; Yu, Cheng-Rong; Garzione, G; Kennedy, Michael C; Wawrousek, Eric; Gee, Michelle L

Description

We have previously shown that transgenic (Tg) mice expressing either soluble or membrane-bound hen egg lysozyme (sHEL or mHEL, respectively) under control of the αA-crystallin promoter develop tolerance due to thymic expression of minuscule amounts of HE

CollectionsANU Research Publications
Date published: 2003
Type: Journal article
URI: http://hdl.handle.net/1885/86183
Source: Journal of Immunology

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