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The Role of Endoplasmic Reticulum Stress in Nonimmune Diabetes: NOD.k iHEL, a Novel Model of β Cell Death

Socha, L; Silva, Diego; Lesage, Sylvie; Goodnow, Christopher; Petrovsky, Nikolai

Description

The final common pathway in diabetes development is β cell apoptosis. We herein describe a novel diabetes model based on transgenic NOD.k iHEL mice, wherein male mice develop diabetes due to nonimmune-mediated β cell death. Histology and electron micros

CollectionsANU Research Publications
Date published: 2003
Type: Journal article
URI: http://hdl.handle.net/1885/86166
Source: Annals of the New York Academy of Sciences
DOI: 10.1196/annals.1288.022

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