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Relative toxicity of venlafaxine and selective serotonin reuptake inhibitors in overdose compared to tricyclic antidepressants

Whyte, Ian M; Dawson, Andrew; Buckley, Nicholas


Background: Selective serotonin reuptake inhibitors (SSRIs) and venlafaxine have been regarded as less toxic in overdose than tricyclic antidepressants (TCAs). Within the TCAs, dothiepin has greater toxicity. Venlafaxine may be more toxic than SSRIs. Aim: To assess the toxicity in overdose of venlafaxine and SSRIs compared to TCAs, and of dothiepin compared to other TCAs. Design: Cohort study of prospectively collected data from the Hunter area, NSW, Australia. Methods: First admissions with...[Show more]

CollectionsANU Research Publications
Date published: 2003
Type: Journal article
Source: QJM
DOI: 10.1093/qjmed/hcg062


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