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Generalized resistance to thymic deletion in the NOD mouse: A polygenic trait characterized by defective induction of Bim

Liston, Adrian; Lesage, Sylvie; Gray, Derek; O'Reilly, Lorraine A; Strasser, Andreas; Fahrer, Aude; Boyd, Richard L; Wilson, Judith; Baxter, Alan G; Gallo, Elena; Crabtree, Gerald R; Peng, Kaimen; Wilson, Susan; Goodnow, Christopher

Description

The cause of common polygenic autoimmune diseases is not understood because of genetic and cellular complexity. Here, we pinpoint the action of a subset of autoimmune susceptibility loci in the NOD mouse strain linked to D1mit181, D2mit490, D7mit101, and

CollectionsANU Research Publications
Date published: 2004
Type: Journal article
URI: http://hdl.handle.net/1885/85984
Source: Immunity
DOI: 10.1016/j.immuni.2004.10.014

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