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The Mitogen-Induced Increase in T Cell Size Involves PKC and NFAT Activation of Rel/NF-kB-Dependent c-myc Expression

Grumont, Raelene; Lock, Peter; Shannon, M Frances; Moore, Anna; Gerondakis, Steve; Mollinari, Michael


Cell growth during the G1 stage of the cell cycle is partly controlled by inducing c-myc expression, which in B cells is regulated by the NF-κB1 and c-Rel transcription factors. Here, we show that c-myc-dependent growth during T cell activation requires

CollectionsANU Research Publications
Date published: 2004
Type: Journal article
Source: Immunity
DOI: 10.1016/j.immuni.2004.06.004


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