Widespread failure of hematolymphoid differentiation caused by a recessive niche-filling allele of the Ikaros Transcription Factor
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Papathanasiou, Panagiotis; Perkins, Andrew C; Cobb, Bradley S; Ferrini, Roger; Sridharan, Rupa; Hoyne, Gerard; Nelms, Keats; Smale, Stephen T; Goodnow, Christopher
Description
A central issue in understanding the hematolymphoid system is the generation of appropriate mutant alleles in mice to reveal the function of regulatory genes. Here we describe a mouse strain, Plastic, with a point mutation in a zinc finger of Ikaros that
dc.contributor.author | Papathanasiou, Panagiotis | |
---|---|---|
dc.contributor.author | Perkins, Andrew C | |
dc.contributor.author | Cobb, Bradley S | |
dc.contributor.author | Ferrini, Roger | |
dc.contributor.author | Sridharan, Rupa | |
dc.contributor.author | Hoyne, Gerard | |
dc.contributor.author | Nelms, Keats | |
dc.contributor.author | Smale, Stephen T | |
dc.contributor.author | Goodnow, Christopher | |
dc.date.accessioned | 2015-12-13T23:06:05Z | |
dc.identifier.issn | 1074-7613 | |
dc.identifier.uri | http://hdl.handle.net/1885/85855 | |
dc.description.abstract | A central issue in understanding the hematolymphoid system is the generation of appropriate mutant alleles in mice to reveal the function of regulatory genes. Here we describe a mouse strain, Plastic, with a point mutation in a zinc finger of Ikaros that | |
dc.publisher | Cell Press | |
dc.source | Immunity | |
dc.subject | Keywords: DNA; Ikaros transcription factor; transcription factor; unclassified drug; allele; animal cell; animal experiment; animal tissue; article; cell differentiation; cell maturation; complex formation; controlled study; DNA binding; embryo; embryo development; | |
dc.title | Widespread failure of hematolymphoid differentiation caused by a recessive niche-filling allele of the Ikaros Transcription Factor | |
dc.type | Journal article | |
local.description.notes | Imported from ARIES | |
local.description.refereed | Yes | |
local.identifier.citationvolume | 19 | |
dc.date.issued | 2003 | |
local.identifier.absfor | 110704 - Cellular Immunology | |
local.identifier.ariespublication | MigratedxPub14526 | |
local.type.status | Published Version | |
local.contributor.affiliation | Papathanasiou, Panagiotis, College of Medicine, Biology and Environment, ANU | |
local.contributor.affiliation | Perkins, Andrew C, Monash University | |
local.contributor.affiliation | Cobb, Bradley S, University of California | |
local.contributor.affiliation | Ferrini, Roger, University of California | |
local.contributor.affiliation | Sridharan, Rupa, University of California | |
local.contributor.affiliation | Hoyne, Gerard, College of Medicine, Biology and Environment, ANU | |
local.contributor.affiliation | Nelms, Keats, College of Medicine, Biology and Environment, ANU | |
local.contributor.affiliation | Smale, Stephen T, University of California | |
local.contributor.affiliation | Goodnow, Christopher, College of Medicine, Biology and Environment, ANU | |
local.description.embargo | 2037-12-31 | |
local.bibliographicCitation.startpage | 131 | |
local.bibliographicCitation.lastpage | 144 | |
local.identifier.doi | 10.1016/S1074-7613(03)00168-7 | |
dc.date.updated | 2015-12-12T08:03:35Z | |
local.identifier.scopusID | 2-s2.0-0038106526 | |
Collections | ANU Research Publications |
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