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Widespread failure of hematolymphoid differentiation caused by a recessive niche-filling allele of the Ikaros Transcription Factor

Papathanasiou, Panagiotis; Perkins, Andrew C; Cobb, Bradley S; Ferrini, Roger; Sridharan, Rupa; Hoyne, Gerard; Nelms, Keats; Smale, Stephen T; Goodnow, Christopher


A central issue in understanding the hematolymphoid system is the generation of appropriate mutant alleles in mice to reveal the function of regulatory genes. Here we describe a mouse strain, Plastic, with a point mutation in a zinc finger of Ikaros that

CollectionsANU Research Publications
Date published: 2003
Type: Journal article
Source: Immunity
DOI: 10.1016/S1074-7613(03)00168-7


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