A cyclodextrin-based molecular reactor to template the formation of indigoid dyes

Abstract

N,N′-Bis(6A-deoxy-β-cyclodextrin-6 A-yl)urea behaves as a molecular reactor to bias competing reactions of indoxyl anion and isatin-5-sulfonate in water, to give indigo and indirubin-5′-sulfonate. It appears that the cyclodextrin dimer increases the