Use of γ-inulin/liposomes/Vitamin E adjuvant combination in contraceptive vaccines
The adjuvanticity of two gamma inulin/liposomes/Vitamin E combinations was evaluated in the mouse, in contraceptive vaccines with sperm protein extracts or a synthetic HE2 peptide ("Human Epididymis gene product"; residues 15-28) as antigen. The HE2 peptide was not conjugated to a protein carrier, to ensure that the antibodies elicited were specific against the HE2 peptide. The adjuvant combinations were designed to increase adjuvanticity, as their components have complementary mechanisms, and...[Show more]
|Collections||ANU Research Publications|
|Source:||International Journal of Pharmaceutics|
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