Skip navigation
Skip navigation

Multiple Actions of Imperatoxin A on Ryanodine Receptors - Interactions with the II-III Loop A Fragment*

Dulhunty, Angela; Curtis, Suzanne; Watson, Sarah; Cengia, Louise; Casarotto, Marco


Imperatoxin A is a high affinity activator of ryanodine receptors. The toxin contains a positively charged surface structure similar to that of the A fragment of skeletal dihydropyridine receptors (peptide A), suggesting that the toxin and peptide could bind to a common site on the ryanodine receptor. However, the question of a common binding site has not been resolved, and the concentration dependence of the actions of the toxin has not been fully explored. We characterize two novel high...[Show more]

CollectionsANU Research Publications
Date published: 2004
Type: Journal article
Source: Journal of Biological Chemistry
DOI: 10.1074/jbc.M310466200


File Description SizeFormat Image
01_Dulhunty_Multiple_Actions_of_2004.pdf692.2 kBAdobe PDF    Request a copy

Items in Open Research are protected by copyright, with all rights reserved, unless otherwise indicated.

Updated:  17 November 2022/ Responsible Officer:  University Librarian/ Page Contact:  Library Systems & Web Coordinator