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Peptide fragments of the dihydropyridine receptor can modulate cardiac ryanodine receptor channel activity and sarcoplasmic reticulum Ca2+ release

Dulhunty, Angela; Curtis, Suzanne; Cengia, Louise; Sakowska, Magdalena; Casarotto, Marco


We show that peptide fragments of the dihydropyridine receptor II-III loop alter cardiac RyR (ryanodine receptor) channel activity in a cytoplasmic Ca 2+-dependent manner. The peptides were Ac (Thr-793-Ala-812 of the cardiac dihydropyridine receptor), As

CollectionsANU Research Publications
Date published: 2004
Type: Journal article
Source: Biochemical Journal
DOI: 10.1042/BJ20031096


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