A/T-targeted somatic hypermutation: critique of the mainstream model
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Blanden, Robert; Franklin, Andrew
Description
The 'affinity maturation' of the humoral immune response is driven by antigen-activated somatic hypermutation (SHM) of the genes that encode antibody variable regions and the subsequent antigenic selection of mutant clones. The molecular mechanism of SHM
| Collections | ANU Research Publications |
|---|---|
| Date published: | 2006 |
| Type: | Journal article |
| URI: | http://hdl.handle.net/1885/85272 |
| Source: | Trends in Biochemical Sciences |
| DOI: | 10.1017/S1047951106000321 |
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| File | Description | Size | Format | Image |
|---|---|---|---|---|
| 01_Blanden_A/T-targeted_somatic_2006.pdf | 59.11 kB | Adobe PDF | Request a copy |
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