Dose-response relationship of DNA and recombinant fowlpox virus prime-boost HIV vaccines: Implications for future trials
De Rose, Robert; Sullivan, Mark T; Dale, C Jane; Kelleher, Anthony D; Emery, Sean; Cooper, David A.; Ramshaw, Ian; Boyle, David B; Kent, Stephen J
Estimating effective doses of novel HIV vaccines is challenging. Dose-response analyses of DNA and fowlpox virus HIV vaccines showed that 1 mg of DNA vaccine and 5 × 107 pfu of fowlpox virus booster was immunogenic in macaques. However, this dose was poo
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