CD8 T cells expressing killer Ig-like receptors and NKG2A are present in cord blood and express a more naive phenotype than their counterparts in adult blood
We report that natural killer receptors (NKR) for major histocompatibility complex (MHC) class I molecules (MHC-NKR), the inhibitory killer immunoglobulin-like receptors (KIR), and the CD94/NKG2A receptor are present on a small proportion of CD8 T cells in cord blood. On average, 1.67% of CD8 T cells in cord blood express KIR, and 0.74% expresses NKG2A, approximately five-fold less than in adult blood. CD8 T cells expressing MHC-NKR were present at similar levels in cord blood from preterm and...[Show more]
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|Source:||Journal of Leukocyte Biology|
|Warren_et_al-2006-Journal_of_Leukocyte_Biology.pdf||564.84 kB||Adobe PDF|
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