Prime-Boost Strategies in DNA Vaccines
Dale, C Jane; Thomson, Scott; De Rose, Robert; Medveczky, C; Pamungkas, Joko; Boyle, David B; Ramshaw, Ian; Kent, Stephen J; Ranasinghe, Charani
Induction of HIV-specific T-cell responses by vaccines may facilitate efficient control of HIV replication. Plasmid DNA vaccines and recombinant fowlpox virus (rFPV) vaccines are promising HIV-1 vaccine candidates, although delivering either vaccine alone may be insufficient to induce sufficient T-cell responses. A consecutive immunization strategy, known as "prime-boost," involving priming with DNA and boosting with rFPV vaccines encoding multiple common HIV antigens, is used to induce broad...[Show more]
|Collections||ANU Research Publications|
|Book Title:||DNA Vaccines: Methods and Protocols (2nd ed)|
|01_Dale_Prime-Boost_Strategies_in_DNA_2006.pdf||1.89 MB||Adobe PDF||Request a copy|
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