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Two Families of Rep-Like Genes That Probably Originated by Interspecies Recombination Are Represented in Viral, Plasmid, Bacterial, and Parasitic Protozoan Genomes

Gibbs, Mark; Smeianov, Vladimir; Steele, James; Upcroft, Peter; Efimov, Boris


Two families of genes related to, and including, rolling circle replication initiator protein (Rep) genes were defined by sequence similarity and by evidence of intergene family recombination. The Rep genes of circoviruses were the best characterized members of the "RecRep1 family." Other members of the RecRep1 family were Rep-like genes found in the genomes of the Canarypox virus, Entamoeba histolytica, and Giardia duodenalis and in a plasmid, p4M, from the Gram-positive bacterium,...[Show more]

CollectionsANU Research Publications
Date published: 2006
Type: Journal article
Source: Molecular Biology and Evolution
DOI: 10.1093/molbev/msj122


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