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Immune cell transcriptome datasets reveal novel leukocyte subset-specific genes and genes associated with allergic processes

Liu, Sue; Ramnik, Xavier; Good, Kim; Chtanova, Tatyana; Newton, Rebecca; Sisavanh, Mary; Zimmer, Sabine; Deng, Chaoyang; Silva, Diego; Frost, Melinda; Tangye, Stuart G; Rolph, Michael; Mackay, Charles R

Description

Background: The precise function of various resting and activated leukocyte subsets remains unclear. For instance, mast cells, basophils, and eosinophils play important roles in allergic inflammation but also participate in other immunologic responses. One strategy to understand leukocyte subset function is to define the expression and function of subset-restricted molecules. Objective: To use a microarray dataset and bioinformatics strategies to identify novel leukocyte markers as well as...[Show more]

CollectionsANU Research Publications
Date published: 2006
Type: Journal article
URI: http://hdl.handle.net/1885/85153
Source: Journal of Allergy and Clinical Immunology
DOI: 10.1016/j.jaci.2006.04.040

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