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The X and Y chromosomes assemble into H2A.Z, containing facultative heterochromatin, following meiosis

Greaves, Ian; Rangasamy, Danny; Devoy, Michael; Graves, Jennifer; Tremethick, David

Description

Spermatogenesis is a complex sequential process that converts mitotically dividing spermatogonia stem cells into differentiated haploid spermatozoa. Not surprisingly, this process involves dramatic nuclear and chromatin restructuring events, but the nature of these changes are poorly understood. Here, we linked the appearance and nuclear localization of the essential histone variant H2A.Z with key steps during mouse spermatogenesis. H2A.Z cannot be detected during the early stages of...[Show more]

CollectionsANU Research Publications
Date published: 2006
Type: Journal article
URI: http://hdl.handle.net/1885/85151
Source: Molecular and Cellular Biology
DOI: 10.1128/MCB.00519-06

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