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Malaria parasite proteins that remodel the host erythrocyte

Maier, Alex; Cooke, Brian M.; Cowman, A; Tilley, Leann

Description

Exported proteins of the malaria parasite Plasmodium falciparum interact with proteins of the erythrocyte membrane and induce substantial changes in the morphology, physiology and function of the host cell. These changes underlie the pathology that is responsible for the deaths of 1-2 million children every year due to malaria infections. The advent of molecular transfection technology, including the ability to generate deletion mutants and to introduce fluorescent reporter proteins that track...[Show more]

CollectionsANU Research Publications
Date published: 2009
Type: Journal article
URI: http://hdl.handle.net/1885/84944
Source: Nature Reviews Microbiology
DOI: 10.1038/nrmicro2110

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