Skip navigation
Skip navigation

Human coronavirus OC43 causes influenza-like illness in residents and staff of aged-care facilities in Melbourne, Australia

Birch, C J; Clothier, H; Seccull, A; Tran, Thao (Thomas); Catton, M C; Lambert, Stephen; Druce, J D

Description

Three outbreaks of respiratory illness associated with human coronavirus HCoV-OC43 infection occurred in geographically unrelated aged-care facilities in Melbourne, Australia during August and September 2002. On clinical and epidemiological grounds the outbreaks were first thought to be caused by influenza virus. HCoV-OC43 was detected by RT-PCR in 16 out of 27 (59%) specimens and was the only virus detected at the time of sampling. Common clinical manifestations were cough (74%), rhinorrhoea...[Show more]

dc.contributor.authorBirch, C J
dc.contributor.authorClothier, H
dc.contributor.authorSeccull, A
dc.contributor.authorTran, Thao (Thomas)
dc.contributor.authorCatton, M C
dc.contributor.authorLambert, Stephen
dc.contributor.authorDruce, J D
dc.date.accessioned2015-12-13T23:02:16Z
dc.identifier.issn0950-2688
dc.identifier.urihttp://hdl.handle.net/1885/84811
dc.description.abstractThree outbreaks of respiratory illness associated with human coronavirus HCoV-OC43 infection occurred in geographically unrelated aged-care facilities in Melbourne, Australia during August and September 2002. On clinical and epidemiological grounds the outbreaks were first thought to be caused by influenza virus. HCoV-OC43 was detected by RT-PCR in 16 out of 27 (59%) specimens and was the only virus detected at the time of sampling. Common clinical manifestations were cough (74%), rhinorrhoea (59%) and sore throat (53%). Attack rates and symptoms were similar in residents and staff across the facilities. HCoV-OC43 was also detected in surveillance and diagnostic respiratory samples in the same months. These outbreaks establish this virus as a cause of morbidity in aged-care facilities and add to increasing evidence of the significance of coronavirus infections.
dc.publisherCambridge University Press
dc.sourceEpidemiology and Infection
dc.subjectKeywords: aged; article; Australia; clinical feature; Coronavirus; coughing; flu like syndrome; geographic distribution; human; Influenza virus; nonhuman; residential home; respiratory tract infection; reverse transcription polymerase chain reaction; rhinorrhea; sa
dc.titleHuman coronavirus OC43 causes influenza-like illness in residents and staff of aged-care facilities in Melbourne, Australia
dc.typeJournal article
local.description.notesImported from ARIES
local.description.refereedYes
local.identifier.citationvolume133
dc.date.issued2005
local.identifier.absfor110308 - Geriatrics and Gerontology
local.identifier.ariespublicationMigratedxPub13052
local.type.statusPublished Version
local.contributor.affiliationBirch, C J, Victorian Infectious Diseases Reference Laboratory
local.contributor.affiliationClothier, H, College of Medicine, Biology and Environment, ANU
local.contributor.affiliationSeccull, A, VIC Department of Human Services
local.contributor.affiliationTran, Thao (Thomas), Victorian Infectious Diseases Reference Laboratory
local.contributor.affiliationCatton, M C, Victorian Infectious Diseases Reference Laboratory
local.contributor.affiliationLambert, Stephen, College of Medicine, Biology and Environment, ANU
local.contributor.affiliationDruce, J D, Victorian Infectious Diseases Reference Laboratory
local.description.embargo2037-12-31
local.bibliographicCitation.issue2
local.bibliographicCitation.startpage273
local.bibliographicCitation.lastpage277
local.identifier.doi10.1017/S0950268804003346
dc.date.updated2015-12-12T07:46:00Z
local.identifier.scopusID2-s2.0-15944408404
CollectionsANU Research Publications

Download

File Description SizeFormat Image
01_Birch_Human_coronavirus_OC43_causes_2005.pdf85.49 kBAdobe PDF    Request a copy


Items in Open Research are protected by copyright, with all rights reserved, unless otherwise indicated.

Updated:  19 May 2020/ Responsible Officer:  University Librarian/ Page Contact:  Library Systems & Web Coordinator