Dimerizations of the wallaby gonadotropin-releasing hormone receptor and its splice variants
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Description
Dimerization between wallaby GnRH-R and its splice variants was examined. A baculovirus-based fluorescence resonance energy transfer (Bv-FRET) assay was used to assess protein-protein interaction between wild type wallaby GnRH-R and splice variants (GnRH-RΔ1 and GnRH-RΔ2). FRET analysis demonstrated that GnRH-R, GnRH-RΔ1 or GnRH-RΔ2 are capable of assembling as homodimers. When GnRH-R is co-expressed with GnRH-RΔ1 or GnRH-RΔ2 splice variants, GnRH-R can form heterodimers with GnRH-RΔ1 and...[Show more]
Collections | ANU Research Publications |
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Date published: | 2005 |
Type: | Journal article |
URI: | http://hdl.handle.net/1885/84799 |
Source: | General and Comparative Endocrinology: an international journal |
DOI: | 10.1016/j.ygcen.2005.06.008 |
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File | Description | Size | Format | Image |
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01_Cheung_Dimerizations_of_the_wallaby_2005.pdf | 605.09 kB | Adobe PDF | Request a copy |
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