Unexpected new roles for heparanase in Type 1 diabetes and immune gene regulation
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Freeman, Craig; Ziolkowski, Andrew; He, Y.Q.; Sutcliffe, Elissa L; Zafar, Anjum; Rao, Sudha; Simeonovic, Charmaine; Parish, Christopher
Description
Heparanase (Hpse) is an endo-β-. d-glucuronidase that degrades the glycosaminoglycan heparan sulfate (HS) in basement membranes (BMs) to facilitate leukocyte migration into tissues. Heparanase activity also releases HS-bound growth factors from the extra
Collections | ANU Research Publications |
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Date published: | 2013 |
Type: | Journal article |
URI: | http://hdl.handle.net/1885/84666 |
Source: | Matrix Biology |
DOI: | 10.1016/j.matbio.2013.02.007 |
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01_Parish_Unexpected_new_roles_for_2013.pdf | 824.02 kB | Adobe PDF | Request a copy |
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