Plasmodium permeomics: membrane transport proteins in the malaria parasite.
Kirk, Kiaran; Martin, Rowena; Broer, Stefan; Howitt, Susan; Saliba, Kevin
Description
Membrane transport proteins are integral membrane proteins that mediate the passage across the membrane bilayer of specific molecules and/or ions. Such proteins serve a diverse range of physiological roles, mediating the uptake of nutrients into cells, the removal of metabolic wastes and xenobiotics (including drugs), and the generation and maintenance of transmembrane electrochemical gradients. In this chapter we review the present state of knowledge of the membrane transport mechanisms...[Show more]
dc.contributor.author | Kirk, Kiaran | |
---|---|---|
dc.contributor.author | Martin, Rowena | |
dc.contributor.author | Broer, Stefan | |
dc.contributor.author | Howitt, Susan | |
dc.contributor.author | Saliba, Kevin | |
dc.date.accessioned | 2015-12-13T23:01:29Z | |
dc.date.available | 2015-12-13T23:01:29Z | |
dc.identifier.issn | 0070-217X | |
dc.identifier.uri | http://hdl.handle.net/1885/84458 | |
dc.description.abstract | Membrane transport proteins are integral membrane proteins that mediate the passage across the membrane bilayer of specific molecules and/or ions. Such proteins serve a diverse range of physiological roles, mediating the uptake of nutrients into cells, the removal of metabolic wastes and xenobiotics (including drugs), and the generation and maintenance of transmembrane electrochemical gradients. In this chapter we review the present state of knowledge of the membrane transport mechanisms underlying the cell physiology of the intraerythrocytic malaria parasite and its host cell, considering in particular physiological measurements on the parasite and parasitized erythrocyte, the annotation of transport proteins in the Plasmodium genome, and molecular methods used to analyze transport protein function. | |
dc.publisher | Springer | |
dc.source | Current Topics in Microbiology and Immunology | |
dc.subject | Keywords: carrier protein; xenobiotic agent; cell function; cell membrane; cell vacuole; cellular distribution; erythrocyte; gene mutation; genome; host cell; malaria; membrane electrophysiology; nonhuman; nutrient uptake; oocyte; parasite isolation; Plasmodium fal | |
dc.title | Plasmodium permeomics: membrane transport proteins in the malaria parasite. | |
dc.type | Journal article | |
local.description.notes | Imported from ARIES | |
local.description.refereed | Yes | |
local.identifier.citationvolume | 295 | |
dc.date.issued | 2005 | |
local.identifier.absfor | 060110 - Receptors and Membrane Biology | |
local.identifier.absfor | 060502 - Infectious Agents | |
local.identifier.ariespublication | MigratedxPub12727 | |
local.type.status | Published Version | |
local.contributor.affiliation | Kirk, Kiaran, College of Medicine, Biology and Environment, ANU | |
local.contributor.affiliation | Martin, Rowena, College of Medicine, Biology and Environment, ANU | |
local.contributor.affiliation | Broer, Stefan, College of Medicine, Biology and Environment, ANU | |
local.contributor.affiliation | Howitt, Susan, College of Medicine, Biology and Environment, ANU | |
local.contributor.affiliation | Saliba, Kevin, College of Medicine, Biology and Environment, ANU | |
local.bibliographicCitation.startpage | 325 | |
local.bibliographicCitation.lastpage | 56 | |
dc.date.updated | 2015-12-12T07:40:43Z | |
local.identifier.scopusID | 2-s2.0-24144442901 | |
Collections | ANU Research Publications |
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