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Alkalinisation for organophosphorus pesticide poisoning (Review)

Roberts, Darren; Buckley, Nicholas


BACKGROUND: Poisoning with organophosphorus pesticides (OPs) is an important cause of morbidity and mortality in all parts of the world, particularly developing countries. The case-fatality ratio for pesticide intentional self-poisoning is around 10-20% even when the standard antidotes (atropine, oximes and benzodiazepines) are used. Alternative treatments have been trialled in an attempt to improve outcomes from acute OP poisoning, one of which is plasma alkalinisation. Animal and preliminary...[Show more]

CollectionsANU Research Publications
Date published: 2005
Type: Journal article
Source: Cochrane Database of Systematic Reviews (CDSR)


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