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Life-threatening interactin between complementary medicines: cyanide toxicity following ingestion of Amygdalin and Vitamin C

Bromley, Jonathan; Hughes, Brett G M; Leong, David C S; Buckley, Nicholas


OBJECTIVE: To describe a case of severe accidental cyanide poisoning following a single ingestion of amygdalin with therapeutic intent. CASE SUMMARY: A 68-year-old patient with cancer presented to the emergency department shortly after her first dose (3 g) of amygdalin with a reduced Glasgow Coma Score, seizures, and severe lactic acidosis requiring intubation and ventilation. The patient also ingested 4800 mg of vitamin C per day. She responded rapidly to hydroxocobalamin treatment. The...[Show more]

CollectionsANU Research Publications
Date published: 2005
Type: Journal article
Source: The Annals of Pharmacotherapy
DOI: 10.1345/aph.1E634


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