Glutathione transferases: new functions.
Well known as detoxification enzymes, the glutathione transferases also function in prostaglandin and steroid hormone synthesis. New uses for the canonical glutathione transferase fold are becoming apparent; the bacterial stringent starvation protein SspA and the yeast prion protein Ure2p (both transcription factors) were found to adopt this fold, but their roles remain unclear. The intracellular chloride ion channel CLIC1 adopts the canonical glutathione transferase fold in its soluble form...[Show more]
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|Source:||Current Opinion in Structural Biology|
|01_Oakley_Glutathione_transferases:_new_2005.pdf||864.61 kB||Adobe PDF||Request a copy|
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