Skip navigation
Skip navigation

Evolution of the gelsolin family of actin-binding proteins as novel transcriptional coactivators

Archer, Stuart; Claudianos, Charles; Campbell, Hugh

Description

The gelsolin gene family encodes a number of higher eukaryotic actin-binding proteins that are thought to function in the cytoplasm by severing, capping, nucleating or bundling actin filaments. Recent evidence, however, suggests that several members of the gelsolin family may have adopted unexpected nuclear functions including a role in regulating transcription. In particular, flightless I, supervillin and gelsolin itself have roles as coactivators for nuclear receptors, despite the fact that...[Show more]

CollectionsANU Research Publications
Date published: 2005
Type: Journal article
URI: http://hdl.handle.net/1885/84057
Source: Bioessays
DOI: 10.1002/bies.20200

Download

File Description SizeFormat Image
01_Archer_Evolution_of_the_gelsolin_2005.pdf253.03 kBAdobe PDF    Request a copy


Items in Open Research are protected by copyright, with all rights reserved, unless otherwise indicated.

Updated:  23 August 2018/ Responsible Officer:  University Librarian/ Page Contact:  Library Systems & Web Coordinator